"Blend of Itzel and Isabella"
The name Itzabella is commonly a female name from the "American" origin.
Itzabella is a modern formation that joins the opening of Itzel to the established name Isabella. It first appears in United States birth records in 2007, which points to a recent American coinage rather than an inherited name.
The pronunciation of Itzabella is its-uh-BEL-uh.