"Blend of Sher and -lene"
The name Sherlene is commonly a female name from the "English" origin.
Sherlene belongs to the group of English-language names formed with the -lene ending, alongside Charlene, Darlene and Marlene, all of which appear in the same era. The first element matches the Sher- of Sherry and Sheryl. The name is best described as a twentieth-century American formation from those two name elements rather than as an inherited name with a translated meaning; neither element carries a meaning apart from the names it comes from.
The pronunciation of Sherlene is sher-LEEN.