"Blend of Ty and Keisha"
The name Tykeisha is commonly a female name from the "American" origin.
Tykeisha is a modern American formation built from the name part Ty, as in Tyler and Tyrone, and the ending -keisha found in twentieth-century American names such as Keisha, Takeisha and Lakeisha. The first US birth record for it is 1973, which places it in that later American coinage pattern rather than in an older inherited name. It has no recorded meaning in any language.
The pronunciation of Tykeisha is tye-KEE-shuh.