"Variant of De Luca"
The name Deluca is commonly a male name from the "Italian" origin.
Deluca is an American spelling, written without the space, of the Italian surname De Luca. The surname is built on the personal name Luca, which derives from the Latin Lucas. Deluca enters United States birth records as a given name in 2016.
The pronunciation of Deluca is duh-LOO-kuh.