"Variant of Isidro"
The name Ysidro is commonly a male name from the "Italian" origin.
Ysidro is a Spanish spelling of Isidro, the Spanish form of the name Isidore. Isidore goes back to Greek Isidoros, commonly analysed as the name of the goddess Isis combined with doron, meaning gift. The initial Y reflects an older Spanish practice of writing an initial I as Y, as in the place name San Ysidro in California.
Isidro means "Gift of Isis|Adored".
The pronunciation of Ysidro is ee-SEE-droh.